- When he was 4, his grandfather gave him his favorite present of all time: a horse.
- His father is Italian. His mother, who is Brazilian, has Portuguese ancestry.
- Favorite actors are Robert De Niro and Al Pacino.
- Supporting part on major TV hit series, Lost, playing survivor "Paulo". (November 2006)
- Father of a girl named Nina with his girlfriend Mel Fronckowiak, born in Rio de Janeiro on May 22, 2017.
- Dubbed the main character of 'Stuart Little'(2000) and 'Stuart Little 2'(2002) in the Brazilian versions.
- Studied Communications in college.
- On People (USA) magazine's '50 Most Beautiful' list [2004].
- Taping a prime time soap opera called "Mulheres Apaixonadas" (Women in Love) on Brazil's Rede Globo network. (April 2003)
- Rodrigo participated in the film "The 33" based on a real-life event happened in Chile, when a gold and copper mine collapsed trapping 33 miners underground for 69 days. The movie was filmed in a mine in Colombia and in the city of Copiapo, the specific place in the north of Chile where this event occurred. Rodrigo performed the role of the Chilean Ministry of Mining Laurence Golborne.
- He studied interpretation in the 'Oficina de Atores da Rede Globo' for one year.
- Filming "A Dona da História". (January 2004)
- Broke up with model Ellen Jabour in 2008, after four years of relationship.
- Parents: Francesco Santoro (engineer) and Maria José Junqueira dos Reis (plastic artist).
- He has a sister named Flávia Junqueira dos Reis Santoro (an architect). She's married to Marco Antônio and they have a son named Frederico (b. October 5th 2006 in Rio de Janeiro).
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